Featured Research Projects

Active Studies

SLATE: Systemic Lupus Associated Tcell Effects

We are conducting a longitudinal study (24 months) to understand the treatment of Lupus among those who have been newly diagnosed with the disease.

Participants must meet American College of Rheumatology criteria for lupus and be diagnosed in the last 12 months without starting immunosuppressive treatment. We are also recruiting patients with established lupus (>1 year since diagnosis) to compare our results between early and longstanding disease. Participants will be asked to complete survey questionnaires and provide blood samples over the course of 3-5 study visits. Parking or transportation vouchers may be provided. Study visits can occur at Orthopedic and Arthritis Center (BWH Main Campus,) Faulkner Hospital or at the Rheumatology clinic at 850 Boylston Street for convenience.

For more information about this study, please contact Eilish Dillon edillon2@bwh.harvard.edu

Funded by: Lupus Research Alliance, NIH-NIAID National Institute of Allergy and Infectious Diseases

ORKIDS: A Double-Blind, Placebo-Controlled Randomized, Multicenter Study to Assess Changes in Omega-3 Index in Erythrocytes and Health Benefit after 24 Weeks of Daily Consumption of AKBM-3031 (Omega-3 Phospholipids from krill), Followed by a 24 Week Open-Label
Extension, in Patients with Systemic Lupus Erythematosus (SLE)

We are currently recruiting for a randomized controlled drug study investigating the health benefits of using krill oil among individuals diagnosed with lupus.

Krill oil is extracted from Antarctic Krill and very similar to fish oil. It is high in certain types of fatty acids (building blocks of the fat in our bodies and in the food we eat). The investigators are hoping to learn if using of krill oil can replenish omega-3
deficiency, and to assess if the treatment has positive effects in SLE patients with regards to disease
activity and/or adverse course of the disease.

For more information on this study, contact Emily Oakes at eoakes@bwh.harvard.edu.

The BWH Lupus Center is pleased to participate in the Lupus Research Alliance’s new clinical research network called LUCIN (Lupus Clinical Investigators Network). We are one of many nationally renowned lupus centers represented in the network. A major goal of LUCIN is to facilitate lupus clinical trials and studies, including trials of new therapies.



Physical and Mental Health and Medication Use among Patients with Lupus (Closed to Enrollment)

We are conducting a research study funded by the Rheumatology Research Foundation to understand changes in mental and physical health and medication use among patients with lupus over 6-8 months.

We are looking for participants who have been diagnosed with lupus and are currently taking a lupus medication. Participants will complete a total of 3 sets of surveys either online or at the time of your rheumatology appointment. Participants will receive either a parking or cafeteria voucher for each completed set of surveys.

For more information about this study, please contact Emily Oakes at eoakes@bwh.harvard.edu.

CALM: Assessing Cardiovascular Risk among Patients with Systemic Lupus Erythematosus (Closed to Enrollment)

This is an observational research study examining cardiovascular risk factors over 6-8 months among patients who have been diagnosed with systemic lupus erythematosus.

Participants must have active lupus disease at time of consent and must not have any known cardiac disease affecting physical activity or have any heart-related symptoms present even at rest. Participants will complete survey questionnaires, provide blood samples and have heart imaging over the course of up to 5 study visits.

Participants will receive up to $200 for study participation and costs of transportation or parking will be covered. Study visits will occur in the BWH Lupus Center and the BWH Shapiro Cardiovascular Center, at the BWH Main Campus.

For more information about this study, please contact Emily Oakes at eoakes@bwh.harvard.edu.